PDF reprints are provided below within the context of [fair use]. Please obtain copies from the publisher if appropriate.
- Liston A, Farr AG, Chen Z, Benoist C, Mathis D, Manley NR, Rudensky AY. (2007) Lack of Foxp3 function and expression in the thymic epithelium. J Exp Med, Epub. [PubMed]
- Liston A, Rudensky AY. (2007) Thymic development and peripheral homeostasis of regulatory T cells. Curr Opin Immunol, Epub. [PubMed]
- Zheng Y, Josefowicz SZ, Kas A, Chu TT, Gavin MA, Rudensky AY. (2007) Genome-wide analysis of Foxp3 target genes in developing and mature regulatory T cells. Nature, 445(7130):936-40. [PubMed] [PDF]
- Williams LM, Rudensky AY. (2007) Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3. Nat Immunol, 8(3):277-84. [PubMed] [PDF]
- Gavin MA, Rasmussen JP, Fontenot JD, Vasta V, Manganiello VC, Beavo JA, Rudensky AY. (2007) Foxp3-dependent programme of regulatory T-cell differentiation. Nature, 445(7129):771-5. [PubMed] [PDF]
- Kim JM, Rasmussen JP, Rudensky AY. (2007) Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice. Nat Immunol, 8(2):191-7. [PubMed] [PDF]
- Marie JC, LiggittD, Rudensky AY. (2006) Cellular mechanisms of fatal early-onset autoimmunity in mice with the T cell-specific targeting of transforming growth factor-beta receptor. Immunity, 25(3):441-54. [PubMed] [PDF]
- Kim JM, Rudensky A. (2006) The role of the transcription factor Foxp3 in the development of regulatory T cells. Immunol Rev, 212:86-98. Review. [PubMed] [PDF]
- Rudensky AY, Gavin M, Zheng Y. (2006) FOXP3 and NFAT: partners in tolerance. Cell, 126(2):253-6. Review. [PubMed] [PDF]
- Gavin MA, Torgerson TR, Houston E, DeRoos P, Ho WY, Stray-Pedersen A, Ocheltree EL, Greenberg PD, Ochs HD, Rudensky AY. (2006) Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development. Proc Natl Acad Sci USA, 103(17):6659-64. [PubMed] [PDF]
- Rudensky AY, Campbell DJ. (2006) In vivo sites and cellular mechanisms of T reg cell-mediated suppression. J Exp Med, 203(3):489-92. [PubMed] [PDF]
- Hsieh CS, Zheng Y, Liang Y, Fontenot JD, Rudensky AY. (2006) An intersection between the self-reactive regulatory and nonregulatory T cell receptor repertoires. Nat Immunol, 7(4):401-10. [PubMed] [PDF]
- Rudensky A, Beers C. (2006) Lysosomal cysteine proteases and antigen presentation. Ernst Schering Res Found Workshop, (56):81-95. Review [PubMed]
- Fontenot JD, Rasmussen JP, Gavin MA, Rudensky AY. (2005) A function for interleukin 2 in Foxp3-expression regulatory T cells. Nat Immunol, 6(11):1142-51. [PubMed] [PDF]
- Fontenot JD, Dooley JL, Farr AG, Rudensky AY. (2005) Developmental regulation of Foxp3 expression during ontogeny. J Exp Med, 202(7):901-6. [PubMed] [PDF]
- Hsing LC, Rudensky AY. (2005) The lysosomal cysteine proteases in MHC class II antigen presentation. Immunol Rev, 207:229-41. Review [PubMed] [PDF]
- Hsieh CS, Rudensky AY. (2005) The role of TCR specificity in naturally arising CD25+CD4+ regulatory T cell biology. Curr Top Microbiol Immunol, 293:25-42. Review [PubMed]
- Kronenberg M, Rudensky A. (2005) Regulation of immunity by self-reactive T cells. Nature, 435(7042):598-604. Review [PubMed] [PDF]
- Marie JC, Letterio JJ, Gavin M, Rudensky AY. (2005) TGF-β1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells. J Exp Med, 201(7):1061-7. [PubMed] [PDF]
- Fontenot JD, Rudensky AY. (2005) A well adapted contrivance: The forkhead family transcription factor Foxp3 and regulatory T cell development. Nat Immunol, 6(4):331-7. [PubMed] [PDF]
- Fontenot JD, Rasmussen JP, Williams LM, Dooley JL, Farr AG, Rudensky AY. (2005) Regulatory T cell lineage specification by the forkhead transcription factor Foxp3. Immunity, 22(3):329-41. [PubMed] [PDF]
- Hsieh CS, Liang Y, Tyznik AJ, Self SG, Liggitt D, Rudensky AY. (2004) Recognition of the peripheral self by naturally arising CD25(+) CD4(+) T cell receptors. Immunity, 21(2):267-77. [PubMed] [PDF]
- Fontenot JD, Rudensky AY. (2004) Molecular aspects of regulatory T cell development. Semin Immunol, 16(2):73-80. [PubMed] [PDF]
- Honey K, Forbush K, Jensen PE, Rudensky AY. (2004) Effect of decreasing the affinity of the class II-associated invariant chain peptide on the MHC class II peptide repertoire in the presence or absence of H-2M. J Immunol, 172(7):4142-50. [PubMed] [PDF]
- Gavin M, Rudensky A. (2003) Control of immune homeostasis by naturally arising regulatory CD4+ T cells. Curr Opin Immunol, 15(6):690-6. [PubMed] [PDF]
- Honey K, Rudensky AY. (2003) Lysosomal cysteine proteases regulate antigen presentation. Nat Rev Immunol, 3(6):472-82. [PubMed] [PDF]
- Fontenot JD, Gavin MA, Rudensky AY. (2003) Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat Immunol, 4(4):330-6. [PubMed] [PDF]
- Beers C, Honey K, Fink S, Forbush K, Rudensky A. (2003) Differential regulation of cathepsin S and cathepsin L in interferon gamma-treated macrophages. J Exp Med, 197(2):169-79. [PubMed] [PDF]
- Honey K, Benlagha K, Beers C, Forbush K, Teyton L, Kleijmeer MJ, Rudensky AY (corresponding author), Bendelac A. (2002) Thymocyte expression of cathepsin L is essential for NK T cell development. Nat Immunol, 3(11):1069-74. [PubMed] [PDF]
- Honey K, Nakagawa T, Peters C, Rudensky AY. (2002) Cathepsin L regulates CD4+ T cell selection independently of its effect on invariant chain: a role in the generation of positively selecting peptide ligands. J Exp Med, 195(10):1349-58. [PubMed] [PDF]
- Barton GM, Beers C, deRoos P, Eastman SR, Gomez ME, Forbush KA, Rudensky AY. (2002) Positive selection of self-MHC-reactive T cells by individual peptide-MHC class II complexes. Proc Natl Acad Sci, 99(10):6397-42. [PubMed] [PDF]
- Hsieh CS, deRoos P, Honey K, Beers C, Rudensky AY. (2002) A role for cathepsin L and cathepsin S in peptide generation for MHC class II presentation. J Immunol, 68(6):2618-25. [PubMed] [PDF]
- Gavin MA, Rudensky AY. (2002) Dual TCR T cells: gaining entry into the periphery. Nat Immunol, 3(2)109-10. [PubMed]
- Gavin MA, Clarke S, Negrou E, Gallegos A, Rudensky AY. (2002) Homeostasis and anergy in CD25+CD4+ regulatory T cells is maintained through multiple signal transduction pathways. Nat Immunol, 3:33-41. [PubMed] [PDF]
- Wong P, Barton GM, Forbush KA, Rudensky AY. (2001) Dynamic tuning of T cell reactivity by self-peptide-major histocompatibility complex ligands. J Exp Med, 193:1179-87. [PubMed] [PDF]
- Clarke SR, Rudensky AY. (2000) Survival and homeostatic proliferation of naive peripheral CD4+ T cells in the absence of self peptide:MHC complexes. J Immunol, 165::2458-64. [PubMed] [PDF]
- Nakagawa TY, Brissette WH, Lira PD, Griffiths RJ, Petrushova N, Stock J, McNeish JD, Eastman SE, Howard ED, Clarke SR, Rosloniec EF, Elliott EA, Rudensky AY. (1999) Impaired invariant chain degradation and antigen presentation and diminished collagen-induced arthritis in cathepsin S null mice. Immunity, 10:207-17. [PubMed] [PDF]
- Barton G, Rudensky AY. (1999) Requirement for diverse, low abundance peptides to drive positive selection of T cells. Science, 283: 67-70. [PubMed] [PDF]
- Nakagawa T, Roth W, Wong P, Nelson A, Farr A, Deussing J, Villadangos JA, Ploegh H, Peters C, Rudensky AY. (1998) Cathepsin L: critical role in Ii degradation and CD4 T cell selection in the thymus. Science, 280: 450-453. [PubMed] [PDF]
- Kovats S, Grubin CE, Eastman S, deRoos P, Dongre A, Van Kaer L, Rudensky AY. (1998) Invariant chain-independent function of H-2M in the formation of endogenous peptide-major histocompatibility complex class II complexes in vivo. J Exp Med, 187:245-251. [PubMed] [PDF]
- Grubin CE, Kovats S, deRoos P, Rudensky AY. (1997) Deficient positive selection of CD4 T cells in mice displaying altered repertoires of MHC class II-bound self-peptides. Immunity, 7:197-208. [PubMed] [PDF]






